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Study identifier: NCT06550141 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Emapalumab Prevention of CAR-T Cell Associated Toxicities

Condition: Large B-cell Lymphoma · Relapsed Non-Hodgkin Lymphoma · Refractory Non-Hodgkin Lymphoma  ·  Sponsor: Marcela V. Maus, M.D.,Ph.D.

PhasePhase 2
Planned participants28
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research study involves assessing the impact of emapalumab as preventative management of CAR-T related cytokine release syndrome in participants with Non-Hodgkin's lymphoma (NHL). The research study involves the following study interventions: * Fludarabine and cyclophosphamide (Lymphodepleting Chemotherapy) * Axicabtagene Ciloleucel * Emapalumab

This description comes directly from the study's public registry record.

Talk to the study team

Matthew Frigault, MD  ·  (617) 643-6175  ·  MFRIGAULT@partners.org

Always discuss trial participation with your own doctor first.

Locations (2)

Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06550141