Condition: Metastatic Malignant Neoplasm in the Bone · Metastatic Malignant Solid Neoplasm · Sponsor: City of Hope Medical Center
This clinical trial tests the safety and effectiveness of a single-dose treatment of biology-guided radiation therapy (BgRT) in treating patients with painful cancer that has spread from where it first started (primary site) to the bone (bone metastases). Bone metastases can result in significant pain and reduction in quality of life. Single fraction radiation therapy (SFRT) can produce equivalent pain relief compared to multi-fraction radiation therapy, but SFRT treatments generally lead to higher rates of retreatment. BgRT is a new and innovative form of radiation delivery that uses a signal generated by positron emission tomography to guide external beam radiation therapy. It is a technology breakthrough that uses live, continuously updated data throughout the entire treatment session to determine exactly where to deliver radiotherapy to biologically active tumors. Giving BgRT may be safe and effective in treating patients with painful bone metastases.
This description comes directly from the study's public registry record.
Yi-Jen Chen, MD · 626-218-4589 · yichen@coh.org
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| City of Hope Medical Center | Duarte, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06549478