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Study identifier: NCT06548399 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease

Condition: Inflammatory Bowel Diseases · Crohn's Disease · Ulcerative Colitis  ·  Sponsor: McMaster University

PhaseN/A
Planned participants15
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The purpose of this study is to investigate whether the gut bacteria in IBD patients cause ongoing abdominal pain, even when the disease is calm. Many inflammatory bowel disease (IBD) patients have this pain, regardless of whether their disease is active or not. This might be linked to an imbalance in gut bacteria. Certain IBD patients with persistent abdominal pain experience increased sensitivity in their gut due to bacteria producing LPC and LPA. Our goal is to explore the connection between bacterial LPC/LPA levels and symptoms in IBD patients with long-lasting abdominal pain. Additionally, we aim to pinpoint the specific bacteria responsible for producing LPC/LPA, which in turn causes chronic abdominal pain in these patients.

This description comes directly from the study's public registry record.

Talk to the study team

Gaston H Rueda, MD  ·  905 521-2100  ·  ruedag@mcmaster.ca

Andrea Nardelli, MD  ·  905-521-2100  ·  nardela@mcmaster.ca

Always discuss trial participation with your own doctor first.

Locations (1)

McMaster UniversityHamilton, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06548399