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Study identifier: NCT06546865 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Slim Sheath 22F Holmium Laser Enucleation of the Prostate (HoLEP) vs 26 F Sheath HoLEP for BPH: RCT

Condition: Benign Prostatic Hyperplasia  ·  Sponsor: Thunder Bay Regional Health Research Institute

PhaseNA
Planned participants142
Who can joinMale, 50 Years to no upper limit
Healthy volunteersNo

About this study

Holmium laser enucleation of the prostate (HoLEP) is routinely performed with 24F, 26F, and 28F laser scopes. Proponents of larger caliber scopes suggest that the larger scope size allows for improved visualization, hemostasis, and operative efficiencies. Proponents of a smaller scope diameter suggest that by eliminating the need for pre-HoLEP urethral dilation to accommodate a larger scope. It has also been proposed that a smaller caliber scope is less traumatic to the urethra resulting in lower rates of bladder neck contracture and urethral stricture disease. Currently, to our knowledge, there are no level one evaluation examining scope size 22F versus 26F sheath in laser enucleation outcomes. The aim of our study is to determine if a smaller diameter scope is associated with improved laser enucleation time, post-operative recovery, rates of same-day discharge, or increasing intra-operative or postoperative complication rates

This description comes directly from the study's public registry record.

Talk to the study team

Rabail Siddiqui  ·  (807) 684-6000  ·  rabail.siddiqui@tbh.net

Shalyn Littlefield  ·  (807) 684-6000  ·  shalyn.littlefield@tbh.net

Always discuss trial participation with your own doctor first.

Locations (1)

Thunder Bay Regional Health Sciences CentreThunder Bay, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06546865