Condition: Non-small Cell Lung Cancer · Sponsor: Sun Yat-sen University
This study is a randomized phase III trial that aiming to investigate the role of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) guided hypofractionated radiotherapy (hypo-RT) in patients with locally advanced non-small cell lung cancer (LA-NSCLC) who are planned to receive hypo-RT combined with concurrent chemotherapy and consolidative immunotherapy. Patients will be randomized in a 1:1 ratio into two groups: 1. The study group will undergo adaptive dose-painting hypo-RT based on DCE-MRI. 2. The control group will undergo hypo-RT based on enhanced CT. The treatment-related toxicity, local control and long-term survival will be evaluated compared between MRI-guided and CT-guided hypo-RT.
This description comes directly from the study's public registry record.
Bo Qiu, MD · 02087343031 · qiubo@sysucc.org.cn
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| Sun Yat-sen University Cancer Center | Guangzhou, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06545747