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Study identifier: NCT06544447 Synced from ClinicalTrials.gov · July 29, 2026
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Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction

Condition: Dry Eye  ·  Sponsor: Beijing Tongren Hospital

PhasePhase 1/Phase 2
Planned participants135
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Objective: To evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) for the patients with dry eye disease with meibomian gland dysfunction. Methods: We enrolled 270 patients at Beijing Tongren Hospital. All treatments were self-administered by the patients at home after training at the hospital. Patients completed questionnaires at baseline, 1 month, 3 months, and 6 months. OSDI score, TBUT, OPAS, NPSI-eye, and Schirmer I expressibility and secretion score to evaluate the therapeutic effects. A difference of P \< 0.05 was considered statistically significant.

This description comes directly from the study's public registry record.

Talk to the study team

Dong Wu, Doctor  ·  8613810988682  ·  wudong0120@outlook.com

Haihong Lian, Doctor  ·  8618811612190  ·  lianhh123@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

China Beijing TongRen Hospital, Capital Medical University Beijing, ChinaBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06544447