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Study identifier: NCT06543836 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

ctDNA-guided Treatment of TKI Plus PD-1 Inhibitor for Advanced pMMR/MSS Colorectal Cancer

Condition: Metastatic Colorectal Cancer  ·  Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences

PhasePhase 2
Planned participants68
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The efficacy of combining TKI with PD-1 inhibitor in the treatment of advanced MSS/pMMR colorectal cancer with low levels of maxVAF in peripheral blood ctDNA failed with standard treatment was assessed, compared to standard treatment as chosen by researchers.

This description comes directly from the study's public registry record.

Talk to the study team

Aiping Zhou, M.D.  ·  8610-13691161998  ·  zhouap1825@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06543836