← Eichor
Study identifier: NCT06539741 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Variability in Analgesic Response to Ibuprofen

Condition: Impacted Third Molar Tooth · Pain, Acute  ·  Sponsor: University of Pennsylvania

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, are recommended as first-line treatment for post-surgical dental pain. However, there is variability in analgesic response, and some patients require supplemental opioids for adequate pain relief. The goal of this study is to identify the factors that contribute to the need for opioid after third molar extraction to help limit unnecessary opioid prescriptions in patients who will have good pain relief with ibuprofen alone.

This description comes directly from the study's public registry record.

Talk to the study team

Stacey Secreto  ·  215-746-8871  ·  secreto@upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Pennsylvania School of Dental MedicinePhiladelphia, Pennsylvania, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06539741