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Study identifier: NCT06539208 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase I/IIa,Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Condition: Transthyretin Amyloidosis Polyneuropathy · Transthyrexin Amyloidosis Cardiomyopathy  ·  Sponsor: YolTech Therapeutics Co., Ltd

PhasePhase 1/Phase 2
Planned participants31
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This study will be conducted to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of YOLT-201 in participants with hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) and participants with hereditary transthyretin amyloidosis with cardiomyopathy (ATTRv-CM).

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (3)

Peking Union Medical College HospitalBeijing, Beijing Municipality, ChinaRecruiting
The Second Xiangya Hospital of Central South UniversityChangsha, Hunan, ChinaRecruiting
The First Affiliated Hospital, School of Medicine, Zhejiang UniversityHanzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06539208