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Study identifier: NCT06538480 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Zopa Retreatment and Vector Shedding in Adults With RRP

Condition: Recurrent Respiratory Papillomatosis · Papillomavirus Infection · Papillomaviridae  ·  Sponsor: Precigen, Inc

PhasePhase 4
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This open-label study evaluates safety, vector shedding, and retreatment efficacy of Zopapogene imadenovec (Zopa) in adults with recurrent respiratory papillomatosis (RRP). Two cohorts will be enrolled (n=30): Cohort 1 to assess the magnitude and duration of adenoviral vector shedding in urine, feces, skin, and nasal tissue; Cohort 2 to assess the complete response rate following retreatment.

This description comes directly from the study's public registry record.

Talk to the study team

Head of Clinical Operations  ·  301-556-9900  ·  clinicaltrials@precigen.com

Always discuss trial participation with your own doctor first.

Locations (3)

Winship Cancer Institute, Emory UniversityAtlanta, Georgia, United StatesRecruiting
National Institute of HealthBethesda, Maryland, United StatesRecruiting
University of CincinnatiCincinnati, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06538480