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Study identifier: NCT06538311 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

Condition: Alzheimer Disease · Mild Cognitive Impairment · Logopenic Progressive Aphasia  ·  Sponsor: Massachusetts General Hospital

PhaseEARLY_Phase 1
Planned participants30
Who can joinAll sexes, 40 Years to 99 Years
Healthy volunteersYes

About this study

In this research study we want to learn more about the effects of non-invasive brain stimulation on memory and brain-network function in cognitively unimpaired older adults and in patients with amnestic mild cognitive impairment (aMCI). This study will use a form of non-invasive brain stimulation called repetitive Transcranial Magnetic Stimulation (rTMS). rTMS will slightly alter activity in an area of your brain that controls memory. Changes resulting from this stimulation will be measured with behavioral tests of memory and general cognition, as well as by taking images of your brain with Magnetic Resonance Imaging (MRI). Participants will come in for one baseline visit followed by 10 days of daily rTMS study visits (Monday through Friday) and an evaluation visit. Then, there will be a 2-week break. After this break, they will return for another baseline visit, an additional 10 days of rTMS, and a final evaluation visit.

This description comes directly from the study's public registry record.

Talk to the study team

Alexandra Touroutoglou, PhD  ·  6176436348  ·  atouroutoglou@mgh.harvard.edu

Jordan Walter, BA  ·  6177266207  ·  jwalter2@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06538311