Condition: Gram-negative Bacteremia · Sponsor: Sunnybrook Health Sciences Centre
BALANCE+ is a perpetual multiple domain randomized controlled platform trial to evaluate various treatment strategies for Gram-negative bloodstream infections (GN BSIs). Each domain addresses critical questions in the management of GN BSIs, aiming to refine treatment strategies, enhance patient outcomes, and reduce antimicrobial resistance. The initial vanguard pilot RCT (NCT05893147) started on 29 August 2023 and has successfully completed the pilot phase on 24-Apr-2024. All patients enrolled in the vanguard phase are part of the main platform trial.
This description comes directly from the study's public registry record.
Nick Daneman, MD · 4164806100 · nick.daneman@sunnybrook.ca
Mithun Mohan George · 416-480-6100 · mithun.george@sri.utoronto.ca
Always discuss trial participation with your own doctor first.
| St George Hospital | Kogarah, New South Wales, Australia | Recruiting |
| John Hunter Hospital | New Lambton, New South Wales, Australia | Recruiting |
| Royal Brisbane and Women's Hospital | Herston, Queensland, Australia | Recruiting |
| Redcliffe Hospital | Redcliffe, Queensland, Australia | Recruiting |
| Sunshine Coast University Hospital | Sunshine Coast, Queensland, Australia | Recruiting |
| Monash Medical Center | Clayton, Victoria, Australia | Recruiting |
| Fiona Stanley Hospital | Murdoch, Western Australia, Australia | Recruiting |
| St John of God | Murdoch, Western Australia, Australia | Recruiting |
| Foothills Hospital | Calgary, Alberta, Canada | Recruiting |
| Peter Lougheed Centre | Calgary, Alberta, Canada | Recruiting |
| Rockyview General Hospital | Calgary, Alberta, Canada | Recruiting |
| South Health Campus | Calgary, Alberta, Canada | Recruiting |
+ 27 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06537609