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Study identifier: NCT06536491 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

EC-104 Intravitreal Implant for the Treatment of Diabetic Macular Edema

Condition: Diabetic Macular Edema  ·  Sponsor: Eclipse Life Sciences, Inc.

PhasePhase 1/Phase 2
Planned participants75
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a prospective, randomized, subject- and evaluator-masked, Phase 2, multicenter study comparing the safety and efficacy of EC-104-6M high-dose (fluocinolone acetonide \[FA\] 0.14 mg) implant and EC-104-4M low-dose (FA 0.092 mg) implant to Ozurdex® (dexamethasone intravitreal (IVT) implant, 0.7 mg) in subjects with diabetic retinopathy (DR) and center-involving diabetic macular edema (DME), with prior suboptimal clinical response to IVT anti-VEGF therapy who have been previously treated with locally administered corticosteroids without a clinically significant rise in intraocular pressure (IOP).

This description comes directly from the study's public registry record.

Talk to the study team

Freddie Batalla, MBA  ·  919-443-5542  ·  BETTIS-1@eclipselifesciences.com

Always discuss trial participation with your own doctor first.

Locations (1)

Retina Associates of Florida, LLCTampa, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06536491