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Study identifier: NCT06535568 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38)

Condition: Coronary Disease · Heart Diseases · Cardiovascular Diseases  ·  Sponsor: Fondazione Ricerca e Innovazione Cardiovascolare ETS

PhaseNA
Planned participants576
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This international, multicenter, open-label, randomized clinical trial evaluates the safety and efficacy of single antiplatelet therapy (SAPT) compared to dual antiplatelet therapy (DAPT) in elderly or high bleeding risk patients undergoing percutaneous coronary intervention (PCI) with the latest generation drug-coated balloon (DCB). The study includes patients with stable or unstable coronary syndromes and aims to assess rates of ischemic and bleeding adverse events.

This description comes directly from the study's public registry record.

Talk to the study team

Bernardo Cortese, MD MSc  ·  216-296-9747  ·  bcortese@gmail.com

Beatrice Barbano  ·  segreteria@fondazioneric.org

Always discuss trial participation with your own doctor first.

Locations (1)

IRCCS Auxologico MilanoMilan, MI, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06535568