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Study identifier: NCT06532084 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen

Condition: Acute Myeloid Leukemia, in Relapse · Myelodysplastic Syndromes · Chronic Myeloid Leukemia  ·  Sponsor: St. Petersburg State Pavlov Medical University

PhasePhase 2
Planned participants88
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a single-center randomized open-label phase II clinical trial to compare relapse prophylaxis with sorafenib and observation after graft-versus-host disease prophylaxis with post-transplantation bendamustine and cyclophosphamide in high-risk myeloid malignancies. This is an intention to treat study, where randomization is performed at first documentation of CR after engraftment.

This description comes directly from the study's public registry record.

Talk to the study team

IVAN S MOISEEV  ·  +78123386265  ·  moisiv@mail.ru

Irina V Bykova  ·  +78123386617  ·  bmt-director@1spbgmu.ru

Always discuss trial participation with your own doctor first.

Locations (1)

RM Gorbacheva Research InstituteSaint Petersburg, RussiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06532084