Condition: Lymphoma, T-Cell · NK-LGL Leukemia · T-LGL Leukemia · Sponsor: Institute of Hematology & Blood Diseases Hospital, China
Indolent T/NK-cell lymphomas are a heterogeneous group of lymphoproliferative diseases originating from T/NK cells, characterized by slow growth and proliferation, but currently remain incurable. For indolent T/NK-cell lymphomas that are unresponsive to first-line treatment, there are few treatment options available and the prognosis is poor. This study is an open-label, prospective clinical trial aimed at evaluating the feasibility, efficacy, and safety of PI3K inhibitors in the treatment of relapsed/refractory indolent T/NK-cell lymphomas. Patients will be treated with Linperlisib or Duvelisib, with an expected overall response rate of 60% for PI3K inhibitor treatment.
This description comes directly from the study's public registry record.
Shuhua Yi, Doctor · 86-22-23909106 · yishuhua@ihcams.ac.cn
Lugui Qiu, Doctor · 86-22-23909172 · qiulg@ihcams.ac.cn
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| Institute of Hematology & Blood Diseases Hospital | Tianjin, Tianjin Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06530550