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Study identifier: NCT06530511 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Polatuzumab, Rituximab and Orelabrutinib Combination Regimen (PRO) in the Treatment of Elderly Frail Patients with Treatment-naive Non-GCB DLBCL

Condition: Diffuse Large B Cell Lymphoma  ·  Sponsor: Affiliated Hospital of Nantong University

PhasePhase 2
Planned participants30
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersNo

About this study

This prospective, single-arm, multicenter clinical study aims to enroll 30 frail elderly patients with Non-GCB DLBCL. This study is to evaluate the preliminary efficacy and safety of the combination of Polatuzumab, Rituximab, and orelabrutinib in this population. The primary endpoint is CR rate after induction therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Wenyu Shi  ·  +86 13515203737  ·  shiwenyu@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Affiliated hospital of Nantong UniversityNantong, Jiangsu, ChinaRecruiting
Jiangsu Province HospitalNanjing, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06530511