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Study identifier: NCT06529601 Synced from ClinicalTrials.gov · July 29, 2026
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Comparison Between CAD/CAM and Conventional Mandibular Fixed Retainers.

Condition: Orthodontic Retainers  ·  Sponsor: Azienda Ospedaliero-Universitaria Careggi

PhaseNA
Planned participants54
Who can joinAll sexes, 13 Years to 20 Years
Healthy volunteersNo

About this study

The devices compared in this study are 'retainers', i.e. fixed orthodontic retainers applied to the lingual surface of the central and lateral incisors and lower canines bilaterally. Their function is to maintain dental alignment once fixed orthodontic therapy has ended. In particular, the CAD/CAM device Keeppy patented by the company Leone SpA (Via Ponte a Quaracchi 50, Sesto Fiorentino, Florence) will be compared with the standard retainer made from a steel braided wire (Ortho FlexTech, Reliance Orthodontic Products Inc., 1540 West Thorndale Ave, Itasca, Illinois, USA). This is a single-center, national, controlled, superiority, randomized, crossover, open-label study. The aim of this study is to evaluate whether the CAD/CAM retainer results in fewer failures (fractures or detachments) over a period of 6 months and 2 years compared to the standard retainer. In addition, the aim of the study is to evaluate whether the Keeppy device results in the maintenance of better periodontal health as judged by the use of plaque and bleeding indices on the surfaces of the lower six anterior teeth compared to the standard retainer. Other objectives consist of the patient's assessment of pain, difficulty in speaking and esthetic satisfaction and the stability of the lower anterior tooth sector.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (1)

Orthodontic Clinic, Division of Dentistry, Careggi University HospitalFlorence, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06529601