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Study identifier: NCT06529549 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy and Safety of Organoid-Based Drug Sensitivity Screening to Guide the Treatment of mCRPC Patients Progressed After First-line Treatment

Condition: Metastatic Castration-resistant Prostate Cancer  ·  Sponsor: Sun Yat-sen University

PhaseN/A
Planned participants30
Who can joinMale, 18 Years to 75 Years
Healthy volunteersNo

About this study

This observational study aims to learn about the effects and safety of organoid-based drug sensitivity screening in mCRPC patients with bone metastases that progressed after first-line treatment. The main question it seeks to answer is: Do doctors choose treatment agents based on organoid-based drug sensitivity screening results for mCRPC patients, resulting in a better response? Participants already took bone metastasis biopsies for genetic testing based on current clinical guidelines. This study only takes residual tissue from biopsies for organoid culture.

This description comes directly from the study's public registry record.

Talk to the study team

Yonghong Li, MD  ·  02087343656  ·  liyongh@sysucc.org.cn

Diwei Zhao  ·  15989568094  ·  zhaodw@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06529549