Condition: Depression · Depressive Disorder, Major · Sponsor: The Royal Ottawa Mental Health Centre
Repetitive transcranial magnetic stimulation (rTMS) is a Health Canada approved treatment for major depression. Theta burst stimulation (TBS), a type of rTMS, is a very promising new treatment for major depression in adults and adolescents. However, very few studies have assessed the efficacy of accelerated, three times a day TBS in comparison with standard once a day TBS in adolescents. The study aims to explore further evidence in hopes to conduct a large-scale, randomized, multisite, placebo-controlled clinical trial evaluating the effects of a functional magnetic resonance imaging (fMRI)-guided accelerated rTMS protocol vs. standard once/daily rTMS for treatment-resistant depression in adolescents.
This description comes directly from the study's public registry record.
Stacey Shim, MSc · 613-722-6521 · stacey.shim@theroyal.ca
Maya El-Outa, BSc · 613-722-6521 · Maya.El-Outa@theroyal.ca
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| The Royal's Institute of Mental Health Research | Ottawa, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06528938