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Study identifier: NCT06528730 Synced from ClinicalTrials.gov · July 28, 2026
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A Novel Surgical Criteria for Degenerative Cervical Myelopathy in Chinese Ethnicity

Condition: Degenerative Cervical Spinal Stenosis  ·  Sponsor: The University of Hong Kong

PhaseN/A
Planned participants100
Who can joinAll sexes, 45 Years to no upper limit
Healthy volunteersNo

About this study

Degenerative Cervical Myelopathy (DCM) is an age-related irreversible degenerative disease predominantly affecting the elderly aged 50 and over. DCM is usually triggered by ossification of the posterior longitudinal ligament or ossification of ligamentum flavum or prolapsed intervertebral disc over the cervical spine. Specific clinical signs characterized the presence of cervical spinal cord compression; including Hoffmann's sign, Finger Escape Sign, Scapulohumeral Reflex, and Reverse Supinator Reflex. Hand numbness, clumsiness, and gait disturbance. These are featured clinical manifestations and well-known indicators for detailed clinical and radiographic investigation, such as Magnetic Resonance Imaging (MRI) for diagnosis and surgical planning. Surgical intervention is considered to be the most effective treatment for DCM worldwide. It is the only evidence-based treatment to halt disease progression and allow modest improvement in function and quality of life. DCM progression is not specific to predict the timing for surgery, though it is still debated. Length of symptoms, pre-operative Modified Japanese Orthopaedic Association Scoring System for Cervical Myelopathy (mJOA) and physical performance are suggested as recovery predictors in DCM. In current practice, the offer of surgical treatment is entirely based on the combination of the evidence of cord compression in Magnetic Resonance Imaging (MRI) and mJOA. DCM who are at risk of critical neurological deficits have a …

This description comes directly from the study's public registry record.

Talk to the study team

Karlen Ka-pui Law, M. Phil  ·  29740531  ·  karlenhk@connect.hku.hk

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Locations (1)

The Duchess of Kent Children's Hospital at Sandy BayHong Kong, Hong KongRecruiting

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Source record: clinicaltrials.gov/study/NCT06528730