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Study identifier: NCT06528301 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Condition: Lymphoma, B-Cell · Lymphoma, Non-Hodgkin (NHL) · Lymphoma, Large B-Cell, Diffuse (DLBCL)  ·  Sponsor: Umoja Biopharma

PhasePhase 1
Planned participants106
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a Phase 1 dose-escalation and dose-confirmation study to evaluate the safety and antitumor activity of UB-VV111. The study will enroll patients with relapsed/refractory large B-cell lymphoma (LBCL) and chronic lymphocytic leukemia (CLL).

This description comes directly from the study's public registry record.

Talk to the study team

Jacob Garcia, MD  ·  425-873-8331  ·  jacob.garcia@umoja-biopharma.com

Christine Dehner  ·  christine.dehner@umoja-biopharma.com

Always discuss trial participation with your own doctor first.

Locations (8)

City of HopeDuarte, California, United StatesNot Yet Recruiting
The David and Etta Jonas Center for Cellular TherapyChicago, Illinois, United StatesRecruiting
Washington University School of Medicine/Siteman Cancer CenterSt Louis, Missouri, United StatesRecruiting
University of Nebraska Medical CenterOmaha, Nebraska, United StatesRecruiting
University of Cincinnatti Medical CenterCincinnati, Ohio, United StatesRecruiting
Fred Hutch Cancer CenterSeattle, Washington, United StatesRecruiting
Royal North Shore HospitalSaint Leonards, New South Wales, AustraliaRecruiting
St. Vincent's Hospital MelbourneFitzroy, Victoria, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT06528301