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Study identifier: NCT06527560 Synced from ClinicalTrials.gov · July 29, 2026
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Clinical Trial Comparing Oral Versus Intravenous Cefuroxime in Pregnant Women with Pyelonephritis

Condition: Pyelonephritis in Pregnancy  ·  Sponsor: Hospital de Clinicas de Porto Alegre

PhasePhase 4
Planned participants100
Who can joinFemale, 18 Years to 48 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare rates of cure in pregnant women with pyelonephritis. The main question aims to answer: Can we treat pyelonephritis in pregnancy with oral cefuroxime alone? Pregnant women with pyelonephritis treated with intravenous cefuroxime will be the comparator. Participants will be asked to accept participation in the study and will be randomly allocated to one of the two arms: * Intravenous cefuroxime 750 mg every 8 hours + oral placebo every 12 hours * Oral cefuroxime 500 mg every 12 hours + intravenous saline solution every 8 hours

This description comes directly from the study's public registry record.

Talk to the study team

Ricardo F Savaris, PhD  ·  +55 51 33596042  ·  rsavaris@hcpa.edu.br

Always discuss trial participation with your own doctor first.

Locations (1)

HCPAPorto Alegre, Rio Grande do Sul, BrazilRecruiting

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Source record: clinicaltrials.gov/study/NCT06527560