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Study identifier: NCT06527482 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Autologous Osteoperiosteal Transplantation for the Treatment of Severe Osteochondral Lesions of the Talus

Condition: Osteochondral Lesion of Talus · Autologous Osteoperiosteal Transplantation  ·  Sponsor: Peking University Third Hospital

PhaseN/A
Planned participants60
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to establish a multicenter prospective cohort of patients with severe osteochondral lesion of the talus (OLT), evaluate the clinical efficacy of autologous osteoperiosteal transplantation and the incidence of postoperative donor-site morbidity. The main questions it aims to answer are: Does autologous osteoperiosteal transplantation have good clinical outcomes in the treatment of severe OLT? Does autologous osteoperiosteal transplantation treat severe OLT with fewer postoperative complications? Participants will: Undergo autologous osteoperiosteal transplantation for OLT Receive clinical follow-up 3, 6, 12, and 24 months after surgery and answer scales of ankle function assessment Take CT and MRI preoperatively and 12 and 24 months after surgery

This description comes directly from the study's public registry record.

Talk to the study team

Qinwei Guo, MD  ·  +86 18601129252  ·  guoqinwei@vip.sina.com

Qixian Shen, MD  ·  +86 13318038398  ·  bjmusqx@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Peking University Third HospitalBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06527482