Condition: Metastatic Castration-Resistant Prostate Carcinoma · Stage IVB Prostate Cancer AJCC v8 · Sponsor: University of Washington
This phase II trial tests how well 177Lu-PSMA-617 works in treating patients with prostate cancer that has spread from where it first started (primary site) to other places in the body (metastatic) and that remains despite treatment (resistant). Lutetium Lu 177 (177Lu), the radioactive (tracer) component being delivered by prostate-specific membrane antigen (PSMA)-617, has physical properties that make it ideal radionuclide (imaging tests that uses a small dose tracer) for treatment of metastatic castrate-resistant prostate cancer (mCRPC). 177Lu-PSMA-617 works by binding to prostate cancer cells and inducing damage to deoxyribonucleic acid (DNA) inside prostate cancer cells. Giving 177Lu-PSMA-617 may improve treatment outcomes for patients with mCRPC.
This description comes directly from the study's public registry record.
Akshata Mathur · 206-667-5801 · nucmedresearch@fredhutch.org
Always discuss trial participation with your own doctor first.
| University of California San Francisco | San Francisco, California, United States | Recruiting |
| Olive View-University of California Los Angeles Medical Center | Sylmar, California, United States | Not Yet Recruiting |
| Fred Hutch/University of Washington Cancer Consortium | Seattle, Washington, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06526299