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Study identifier: NCT06526104 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas With Child-Pugh-B Cirrhosis

Condition: Hepatocellular Carcinoma · Cirrhosis, Liver  ·  Sponsor: The University of Texas Health Science Center at San Antonio

PhasePhase 2
Planned participants32
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a single-arm, phase II study of patients with advanced liver cancer or hepatocellular carcinoma (HCC) who are eligible for first-line treatment with T300+D. The invesitgators hypothesize that T300+D will be safe and tolerated in CP-B patients with HCC. HCC mostly affects disadvantaged populations with higher rates among racial/ethnic minorities, who are often not included in clinical trials (i.e., Hispanics, Blacks, underserved, low socioeconomic status) and present with more severe disease. Given there is not much data in the US patient cohort, this study provides a chance to gain that knowledge.

This description comes directly from the study's public registry record.

Talk to the study team

Epp Goodwin  ·  210-450-5798  ·  goodwine@uthscsa.edu

Sukeshi Arora, MD  ·  210-450-2872  ·  aroras@uthscsa.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UT Health San AntonioSan Antonio, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06526104