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Study identifier: NCT06526052 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).

Condition: Prevention · Control  ·  Sponsor: Vanderbilt University

PhaseNA
Planned participants360
Who can joinAll sexes, 12 Years to 17 Years
Healthy volunteersYes

About this study

The goal of this randomized clinical trial is to compare the effects of an online mindfulness program to an active supportive comparison condition and a no-intervention control group on reducing and preventing mood and anxiety symptoms in at-risk youth. Youth who are high on trait negative affect will be randomized to one of the three conditions. The primary outcomes of interest are reductions in momentary negative affect and internalizing problems in adolescents ages 12 to 17 years old. All participants will be evaluated prior to being randomized, after the 9-session intervention period, and at a 6-month follow-up. The first hypothesis is that the mindfulness intervention will predict decreases in stressor-reactive momentary negative affect and internalizing symptoms. The second hypothesis is that changes in momentary negative affect will partially account for the effects of the mindfulness intervention on internalizing symptoms.

This description comes directly from the study's public registry record.

Talk to the study team

Judith A Garber, PhD  ·  6153305605  ·  jgarber.vanderbilt@gmail.com

Steven D Hollon, PhD  ·  6153305604  ·  steven.d.hollon@vanderbilt.edu

Always discuss trial participation with your own doctor first.

Locations (3)

University of California, Los AngelesLos Angeles, California, United StatesRecruiting
Northwestern UniversityEvanston, Illinois, United StatesRecruiting
Vanderbilt UniversityNashville, Tennessee, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06526052