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Study identifier: NCT06525571 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection

Condition: Bladder Cancer  ·  Sponsor: Johns Hopkins University

PhasePhase 3
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Comparing white-light cystoscopy (WLC) and blue-light cystoscopy (BLC) in TURBT for high risk (HR) non-muscle invasive bladder cancer (NMIBC) patients is crucial to determine the most effective method for reducing residual disease burden and improving recurrence-free survival. Enhanced visualization with BLC may lead to more accurate resections, potentially decreasing recurrence rates and improving long-term outcomes for bladder cancer patients. Patients will be randomized to either WLC TURBT or BLC TURBT, and outcomes will be measured using standard-of-care testing with cystoscopy and cytology, along with minimal residual disease (MRD) burden evaluation using urine next-generation sequencing.

This description comes directly from the study's public registry record.

Talk to the study team

Domani Rodriguez  ·  2026605561  ·  drodri59@jh.edu

Armine Smith, MD  ·  2026605561  ·  asmit165@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Sibley Memorial HospitalWashington D.C., District of Columbia, United StatesRecruiting
Johns Hopkins University School of MedicineBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06525571