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Study identifier: NCT06523400 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Efficacy and Safety of Once Daily Mexiletine PR in Patients With Myotonic Dystrophy Type 1 and Type 2

Condition: Myotonic Dystrophy  ·  Sponsor: Lupin Ltd.

PhasePhase 3
Planned participants176
Who can joinAll sexes, 16 Years to no upper limit
Healthy volunteersNo

About this study

A Randomized, Double-blind, Placebo-Controlled, Multi-Center Study to Investigate the Efficacy and Safety of Once Daily Mexiletine PR During 26 Weeks of Treatment in Patients with Myotonic Dystrophy Type 1 and Type 2 (HERCULES study)

This description comes directly from the study's public registry record.

Talk to the study team

Nikki Adetoro  ·  1 443-447-4534  ·  nikkiadetoro@lupin.com

Always discuss trial participation with your own doctor first.

Locations (7)

Laboratory for Muscle Diseases and NeuropathiesLeuven, BelgiumRecruiting
Aarhus University HospitalAarhus, DenmarkRecruiting
Ludug-Maximilians UniversityMünchen, GermanyRecruiting
Azienda Ospedaliera Universitaria Policlinico Tor VergataRome, ItalyRecruiting
University Hospital of MadridMadrid, SpainRecruiting
Saint George's University Hospitals NHS Foundation TrustLondon, United KingdomRecruiting
University College HospitalLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06523400