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Study identifier: NCT06522555 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Efficacy and Safety of Pola-ZR2 Versus ZR2 in the Treatment of Old Patients With de Novo Diffuse Large B-cell Lymphoma

Condition: Diffuse Large B-Cell Lymphoma  ·  Sponsor: Ruijin Hospital

PhasePhase 3
Planned participants100
Who can joinAll sexes, 70 Years to no upper limit
Healthy volunteersNo

About this study

A multicenter, prospective, randomized, open-label, controlled trial to evaluate the efficacy and safety of Pola-ZR2 (polatuzumab vedotin, zanubrutinib, rituximab and lenalidomide) versus ZR2 (zanubrutinib, rituximab and lenalidomide) in the treatment of old patients with de novo diffuse large B-cell lymphoma

This description comes directly from the study's public registry record.

Talk to the study team

Weili Zhao  ·  +862164370045  ·  zwl_trial@163.com

Li Wang  ·  +862164370045  ·  wl_wangdong@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Institute of Hematology, Rui-Jin Hospital affiliated to Shanghai Jiao Tong University School of MedicineShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06522555