Condition: Coronary Artery Disease · Optical Coherence Tomography · Sponsor: First Affiliated Hospital of Xinjiang Medical University
The presence of coronary atherosclerotic vulnerable plaque significantly impacts the clinical outcomes of patients diagnosed with coronary artery disease (CAD). However, the influence of PCSK9 inhibitors on stabilizing coronary atherosclerotic plaques in individuals with early-onset CAD, evaluated through optical coherence tomography (OCT), remains inadequately understood. Moreover, there is a notable absence of relevant randomized controlled trials investigating this phenomenon. This current study represents a single-center, randomized, controlled, open-label trial conducted among Asian patients with early-onset CAD. Its principal objective was to explore the effects of PCSK9 inhibitors on coronary atherosclerotic plaque morphology as assessed by OCT.
This description comes directly from the study's public registry record.
Sen Liu, MD · 09914366872 · 463387160@qq.com
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| First Affiliated Hospital of Xinjiang Medical University | Ürümqi, Xinjiang, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06520904