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Study identifier: NCT06519175 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Infantile Lower Limb Malformations and Deformities

Condition: Deformity of Limb  ·  Sponsor: Istituto Ortopedico Rizzoli

PhaseN/A
Planned participants1000
Who can joinAll sexes, N/A to 18 Years
Healthy volunteersNo

About this study

The skeletal defects of the lower limbs in pediatric age encompass various congenital and acquired conditions that alter bone structure. These alterations can be symmetrical or asymmetrical, with potential consequences such as deformities, short stature, and disability. These condictions may impact not only on the physical and the mental function of the children, but also on their family context. Management often requires a multidisciplinary approach for early diagnosis and treatment. Deformities are heterogeneous and necessitate a personalized therapeutic plan. Currently, in pediatric orthopedic surgery there is a lack of an instrument capable of evaluating all these aspects. The advancement of computer-assisted surgery and artificial intelligence could improve treatment customization and involve patients and families in therapeutic decision-making to prevent complications. This study aims to provide support for clinical practice to promote a systematic, comprehensive, and sequential evaluation of lower limb deformities in developmental age, from which epidemiological data and evidence on treatment approaches used in major referral centers can be extrapolated.

This description comes directly from the study's public registry record.

Talk to the study team

Giovanni Trisolino, MD  ·  0516366  ·  giovanni.trisolino@ior.it

Alessandro Depaoli, MD  ·  alessandro.depaoli@ior.it

Always discuss trial participation with your own doctor first.

Locations (7)

IRCCS Istituto Ortopedico RizzoliBologna, ItalyRecruiting
Istituto Giannina GasliniGenova, ItalyNot Yet Recruiting
Galeazzi Orthopedic InstituteMilan, ItalyNot Yet Recruiting
Policlinico San MatteoPavia, ItalyNot Yet Recruiting
Istituto Nazionale Tumori Regina ElenaRoma, ItalyNot Yet Recruiting
Ospedale Pediatrico Bambino GesùRoma, ItalyNot Yet Recruiting
Istituto Clinico HumanitasRozzano, ItalyNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06519175