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Study identifier: NCT06518564 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Avelumab and M1774 in ARID1A-mutated Endometrial Cancer

Condition: Endometrial Cancer · ARID1A Gene Mutation · Recurrent Endometrial Carcinoma  ·  Sponsor: Panagiotis Konstantinopoulos, MD, PhD

PhasePhase 2
Planned participants25
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this research study is to see if the combination of study drugs avelumab and M1774 is effective and safe for participants with endometrial cancer. The names of the study drugs involved in this study are: * Avelumab (a type of human IgG1 antibody) * M1774 (a type of ATR inhibitor)

This description comes directly from the study's public registry record.

Talk to the study team

Panagiotis Konstantinopoulos, MD, PhD  ·  617-632-5269  ·  Panagiotis_Konstantinopoulos@dfci.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06518564