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Study identifier: NCT06515418 Synced from ClinicalTrials.gov · July 27, 2026
● Terminated

Efficacy and Safety of Oral Azelaprag Plus Once Weekly Tirzepatide Compared with Tirzepatide Alone in Participants with Obesity Aged 55 Years and Over

Condition: Obesity  ·  Sponsor: BioAge Labs, Inc.

PhasePhase 2
Planned participants204
Who can joinAll sexes, 55 Years to no upper limit
Healthy volunteersNo

About this study

This study aims to find out how well a combination of oral azelaprag taken once a day (QD) or twice a day (BID), along with a weekly injection of tirzepatide, works for weight management in adults 55 years and older. The researchers are also looking at safety. Estimated Study Length: * with the optional prescreening, the study duration may be up to 48 weeks. * the treatment duration will be 24 weeks followed by 12 weeks follow-up. * the visit frequency will be every 2 weeks for the first 8 weeks of the treatment period and every 4 weeks thereafter.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (14)

Site 110Mesa, Arizona, United States
Site 107Los Angeles, California, United States
Site 103Montclair, California, United States
Site 105Spring Valley, California, United States
Site 100Louisville, Kentucky, United States
Site 101Marrero, Louisiana, United States
Site 112Boston, Massachusetts, United States
Site 111Troy, Michigan, United States
Site 113City of Saint Peters, Missouri, United States
Site 106Butte, Montana, United States
Site 109Fargo, North Dakota, United States
Site 108Beachwood, Ohio, United States

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06515418