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Study identifier: NCT06514560 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

OPTImizing MIltefosine Treatment for Cutaneous LEISHmaniasis Patients

Condition: Cutaneous Leishmaniases  ·  Sponsor: Institute of Tropical Medicine, Belgium

PhaseN/A
Planned participants80
Who can joinAll sexes, 2 Years to no upper limit
Healthy volunteersNo

About this study

While there are indications that 28 days of miltefosine is not sufficient for treating CL by L. aethiopica, a better understanding of what happens in terms of parasite clearance and drug dosing is lacking. In this study, longitudinal measurements of parasite and drug concentrations during treatment are done to monitor parasite kinetics as well as pharmacokinetics. This data will be crucial to provide more information on duration and dosing of miltefosine in CL patients globally, and in Ethiopia and pediatric patients in particular.

This description comes directly from the study's public registry record.

Talk to the study team

Shimelis Nigusse, MD  ·  0911642060  ·  shimelis321@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Africa Leprosy, Tuberculosis, Rehabilitation and Training (ALERT) HospitalAddis Ababa, EthiopiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06514560