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Study identifier: NCT06514534 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Open-label Study of Asciminib for CML-CP or CML-AP Patients With T315I Mutation Who Are Resistant, Intolerant or Ineligible to Ponatinib.

Condition: Chronic Myeloid Leukemia (CML)  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

The objective of this Phase II study is to assess the potential of asciminib in managing CML-CP or CML-AP in patient carrying the T315I mutation. The presence of this mutation introduces treatment difficulties due to the limited available options. The study seeks to collect additional data on the effectiveness and safety of asciminib for these patients. By determining the drug's capacity to manage the disease and enhance patients outcomes, the study is designed to fill the unmet medical need and potentially offer a new therapeutic path for patients at a treatment deadlock.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  +41613241111  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  novartis.email@novartis.com

Always discuss trial participation with your own doctor first.

Locations (6)

Novartis Investigative SiteBordeaux, FranceRecruiting
Novartis Investigative SiteLille, FranceRecruiting
Novartis Investigative SiteLyon, FranceRecruiting
Novartis Investigative SiteNantes, FranceRecruiting
Novartis Investigative SiteParis, FranceRecruiting
Novartis Investigative SiteVandœuvre-lès-Nancy, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06514534