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Study identifier: NCT06514235 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Image-guided Brachytherapy for Vaginal Cancer (EMBRAVE)

Condition: Vaginal Neoplasms  ·  Sponsor: Erasmus Medical Center

PhaseN/A
Planned participants300
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical study is to improve clinical outcomes of patients with vaginal cancer including vaginal recurrences who are treated with curative intent by primary radio(chemo)therapy and image-guided adaptive brachytherapy (IGABT). Being an observational, prospective registration study, wherein neither an experimental treatment is compared to the standard treatment, nor groups of patients are compared. The specific aims are: * to develop evidence-based recommendations for curative intent treatment with primary radio(chemo)therapy and IGABT. * to identify prognostic parameters for oncological outcomes, morbidity and quality of life. The study aims to enroll at least 300 patients. Oncological events will be evaluated at 2 and 5 years of follow-up. Acute and late morbidity events will be evaluated at end of treatment, 2 and 5 years of follow-up.

This description comes directly from the study's public registry record.

Talk to the study team

Remi A. Nout, PhD  ·  +31107041366  ·  r.nout@erasmusmc.nl

René M. Vernhout, MSc  ·  +31107041341  ·  r.vernhout@erasmusmc.nl

Always discuss trial participation with your own doctor first.

Locations (1)

Erasmus MCRotterdam, South Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06514235