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Study identifier: NCT06513286 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate

Condition: Chronic Hepatitis B  ·  Sponsor: Michael Hoelscher

PhasePhase 1/Phase 2
Planned participants81
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This study is an open-label, ascending dose phase 1b/2a trial to assess the safety and immunogenicity of a heterologous protein prime/MVA boost therapeutic hepatitis B vaccine in patients with chronic HBV who are virally suppressed with oral anti-viral therapies.

This description comes directly from the study's public registry record.

Talk to the study team

Otto Geisenberger, Dr.rer.nat.  ·  +49-89-4400598  ·  otto.geisenberger@med.uni-muenchen.de

Always discuss trial participation with your own doctor first.

Locations (6)

Investigational Site GUFFrankfurt, GermanyRecruiting
Investigational Site UKEHamburg, GermanyRecruiting
Investigational Site MHHHanover, GermanyNot Yet Recruiting
Investigational Site Uni LeipzigLeipzig, GermanyRecruiting
Investigational Site LMUMunich, GermanyRecruiting
Investigational Site TUMMunich, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT06513286