Condition: Graft Failure · Stem Cell Transplant Complications · Sponsor: Peking University People's Hospital
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. There are no recommended regimens for second transplantations for graft failure, especially in the haploidentical transplant setting. We recently reported encouraging outcomes using a novel method (haploidentical transplantation from a different donor after conditioning with fludarabine and cyclophosphamide). However, the study was performed in single-center and with very small sample size. Therefore, it should be further validated via multicenter study. In this multi-center study, we aim to further evaluate the safety and efficacy of this protocol.
This description comes directly from the study's public registry record.
Yu-qian Sun, M.D. · +86-10-88324577 · sunyuqian83@hotmail.com
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| Peking University People's Hospital | Beijing, Beijing Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06512519