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Study identifier: NCT06512181 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Uterine Preservation in the Management of Placenta Accreta Spectrum Disorders

Condition: Placenta Accreta Spectrum  ·  Sponsor: University of Pennsylvania

PhaseNA
Planned participants15
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study for the conservative management of placenta accreta spectrum disorders (PAS), which are a major cause of maternal morbidity and mortality. The most common management strategy for PAS in the United States is a preterm cesarean-hysterectomy. However, accumulating data show that conservative management is safer and is preferred by some patients. In selected participants (n=15) who desire uterine preservation, the investigators provide the option of conservative management, which will be defined as leaving the placenta in the uterus after delivery of the infant. This is a single-arm single-site pilot study where all participants will be carefully monitored during a standard postpartum inpatient stay and with outpatient follow-up until the uterus is empty.

This description comes directly from the study's public registry record.

Talk to the study team

Beth Pineles, MD Phd  ·  267-226-7933  ·  beth.pineles@pennmedicine.upenn.edu

Meaghan McCabe, MPH  ·  meaghan.mccabe@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06512181