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Study identifier: NCT06510868 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy

Condition: Myelodysplastic Syndrome · Acute Myeloid Leukemia  ·  Sponsor: University Health Network, Toronto

PhaseN/A
Planned participants45
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This is a prospective observational study which aims to identify individuals predisposed to developing myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) could improve patient outcomes in different ways. First, it will enable improved patient selection for PRRT where alternative treatment options are available. Second, understanding the final pathway and how it is modulated by PRRT could allow the design of strategies to halt this process. Third, while it is unknown whether the development of MDS and AML is a late effect of radiopharmaceuticals in general or it is confined to cancer populations or specific radioisotopes will need to be confirmed. Finally, understanding this devastating complication is expected to be the cornerstone towards advancing radiopharmaceuticals' role in the adjuvant setting.

This description comes directly from the study's public registry record.

Talk to the study team

Rebecca Wong  ·  416-946-4501  ·  rebecca.wong@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Princess Margaret Cancer CentreToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06510868