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Study identifier: NCT06508931 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Safety and Efficacy Study of Zamtocabtagene Autoleucel (MB-CART2019.1) in Pediatric Patients With R/R B-Cell Neoplasms

Condition: B-Cell Neoplasm  ·  Sponsor: Miltenyi Biomedicine GmbH

PhasePhase 2
Planned participants31
Who can joinAll sexes, 6 Months to 17 Years
Healthy volunteersNo

About this study

This is a single-arm, multi-center, open-label Phase II study to determine the safety and efficacy of MB-CART2019.1 in pediatric and adolescent subjects (aged between 6 months and \<18 years, ≥6 kg body weight \[BW\]) with mature B-cell neoplasms and aggressive lymphomas that relapsed after or are refractory to one or more prior therapies, including subjects with primary refractory disease.

This description comes directly from the study's public registry record.

Talk to the study team

Andrey Shirokov  ·  +49 151 1179 4851  ·  andrey.shirokov@miltenyi.com

Gregor Zadoyan, Dr.  ·  +49 151 4025 8225  ·  gregor.zadoyan@miltenyi.com

Always discuss trial participation with your own doctor first.

Locations (5)

Hôpital Robert DebréParis, Boulevard Sérurier 48, FranceActive Not Recruiting
Institut Gustave RoussyVillejuif, FranceRecruiting
Universitaetsklinikum Muenster (UKM) - Klinik fuer Kinder- und Jugendmedizin - Paediatrische Haematologie und OnkologieMünster, Albert-Schweitzer-Campus 1, Gebaeude A1, GermanyActive Not Recruiting
IRCCS Ospedale Pediatrico Bambino GesùRome, Piazza Sant Onofrio 4, ItalyRecruiting
Prinses Maxima CentrumUtrecht, Heidelberglaan 25, NetherlandsActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT06508931