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Study identifier: NCT06507488 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Daphnetin Capsule In the Treatment of VaScular COgnitive Impairment Without Dementia

Condition: Cerebrovascular Disorders  ·  Sponsor: First People's Hospital of Shenyang

PhaseNA
Planned participants206
Who can joinAll sexes, 50 Years to 80 Years
Healthy volunteersNo

About this study

The purpose of this clinical trial is to understand and evaluate the clinical efficacy and safety of Daphnetin Capsule in patients with vascular cognitive impairment. Changes in the Vascular Dementia Assessment Scale-cog(VADAS-cog) at 6 months were evaluated. Although Daphnetin has a dual neurovascular protective effect, however, there is still a lack of relevant high-quality studies on its role in patients with vascular cognitive impairment, especially in patients with vascular cognitive impairment in non-dementia (VCI-ND), whether it has a role in improving cognitive status needs to be urgently explored in high-quality clinical studies. Researchers are comparing Daphnetin to placebo (a drug-free analog) to see if Daphnetin is effective in treating vascular cognitive impairment. Participants will take either Daphnetin or placebo daily for six months, with follow-up visits every three months and completion of a case report form.

This description comes directly from the study's public registry record.

Talk to the study team

Yi Sui, MD PhD  ·  +86 24 86861329  ·  jakeyisui@icloud.com

Mingming Dong, MD  ·  +86 24 86861329  ·  dongming_ming@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shenyang First People's HospitalShenyang, Liaoning, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06507488