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Study identifier: NCT06507293 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Paravertebral Block and Erector Spinae Plane Block on Intraoperative Opioid Consumption Using NoL Index

Condition: Postoperative Pain · Opioid Use  ·  Sponsor: Kocaeli University

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Thoracotomy is among the most painful surgical procedures and can cause severe pain with a high incidence. Inadequate treatment of acute postoperative pain may lead to undesired complications. Paravertebral block (PVB) is an effective technique that provides adequate analgesia in thoracic surgeries. However, it is an advanced technique with potential complication risks. Erector spinae plane block (ESPB) is a relatively new and considered as a safer technique that provides comparable analgesia. However, the results are controversial and there are few studies that compares the effect of these blocks in thoracic surgeries. As well as the undesired effects of inadequate pain management, high doses of perioperative opioid usage may contribute to the development of dose-dependent long-term adverse events. Hemodynamic parameters are generally used to determine the intraoperative need for opioids in patients; however, hemodynamic parameters are not standardized and they do not provide a clear assessment. The Nociception Level (NoL) index is generated from five different parameters (heart rate, heart Rrate variability, photo-plethysmographic waveform amplitude, skin conductance level, number of skin conductance fluctuations, and their time derivatives) using a finger probe and is a promising monitoring technique. Selecting an effective analgesia method and determining the appropriate dose of opioids using NoL monitoring can reduce perioperative and postoperative complications and shor…

This description comes directly from the study's public registry record.

Talk to the study team

Hadi Ufuk Yörükoğlu  ·  +902623038248  ·  ufukyorukoglu@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Kocaeli UniversityKocaeli, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT06507293