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Study identifier: NCT06506578 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Nausea Induced by Radiation of the Dorsal Vagal Complex for Benign Brain Tumors (NausiCAA)

Condition: Benign Brain Tumor  ·  Sponsor: University Hospital, Bordeaux

PhaseN/A
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Patients irradiated to the brain frequently experience nausea. The dorsal vagal complex (DVC) area is a specific brainstem zone and has been identified as likely responsible for nausea. Existing clinical studies show correlation between dose to the DVC and nausea, but they concern tumors of the airways and upper digestive tract, where there are many confounding factors. The aim of this study is to establish a ling between radiation dose to the DVC and nausea. Defining a dose threshold to the DVC will allow radiation oncologists to optimize radiation dose distribution and reduce nausea in patients.

This description comes directly from the study's public registry record.

Talk to the study team

Charles DUPIN, MD, PhD  ·  :+33(0)557623310  ·  charles.dupin@chu-bordeaux.fr

Always discuss trial participation with your own doctor first.

Locations (3)

CHU de Bordeaux, Service de RadiothérapieBordeaux, FranceRecruiting
Hospices Civils de Lyon, Service d'Oncologie Radiothérapie - Hôpital NeurologiqueLyon, FranceNot Yet Recruiting
Institut de cancérologie Strasbourg Europe (ICANS), Service d'Oncologie RadiothérapieStrasbourg, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06506578