Condition: Atrial Fibrillation (AF) · Sponsor: University College, London
Atrial fibrillation (AF) is a common heart rhythm disorder that causes an irregular heart beat and is a cause of heart failure (HF). Treatments include drugs to slow the heart rate, anti-arrhythmic drugs or ablation of the heart to help preserve normal rhythm. A number of trials have suggested that ablation may be superior to drug treatment to reduce hospitalisations or prevent early death. However, these studies have been small and the results not applicable to the general population with AF and heart failure in the UK. This international study will compare catheter ablation and optimal medical therapy versus optimal medical therapy alone to see if catheter ablation reduces unplanned heart failure hospitalisations and death rates and improves quality of life.
This description comes directly from the study's public registry record.
Pier Lambiase · 07977217787 · p.lambiase@ucl.ac.uk
CRAAFT-HF Team @ Barts CVCTU · craaft-hf-cvctu@qmul.ac.uk
Always discuss trial participation with your own doctor first.
| Halifax Infirmary | Halifax, Canada | Recruiting |
| Mid and South Essex NHS Foundation Trust | Basildon, United Kingdom | Recruiting |
| Queen Elizabeth Hospital | Birmingham, United Kingdom | Recruiting |
| Blackpool Victoria Hospital | Blackpool, United Kingdom | Recruiting |
| University Hospitals Dorset NHS Foundation Trust | Bournemouth, United Kingdom | Recruiting |
| Royal Papworth Hospital NHS Foundation Trust | Cambridge, United Kingdom | Recruiting |
| University Hospitals Coventry and Warwickshire NHS Trust | Coventry, United Kingdom | Recruiting |
| Golden Jubilee National Hospital | Glasgow, United Kingdom | Recruiting |
| Hull University Teaching Hospitals NHS Trust | Hull, United Kingdom | Recruiting |
| Leeds Teaching Hospitals NHS Trust | Leeds, United Kingdom | Recruiting |
| Glenfield Hospital | Leicester, United Kingdom | Recruiting |
| Liverpool Heart and Chest Hospital NHS Foundation Trust | Liverpool, United Kingdom | Recruiting |
+ 12 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06505798