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Study identifier: NCT06505460 Synced from ClinicalTrials.gov · July 28, 2026
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Exploring the Possible Beneficial Impact of Non-invasive and Invasive Neuromodulation on Freezing of Gait in Parkinson's Disease During Different Ambulatory Complexities: An Electrophysiological and fMRI Study

Condition: Transcranial Direct Current Stimulation  ·  Sponsor: China Medical University Hospital

PhaseNA
Planned participants20
Who can joinAll sexes, 20 Years to 90 Years
Healthy volunteersYes

About this study

Freezing of gait (FOG) stands out as a devastating symptom of Parkinson's disease (PD), where patients may become momentarily glued to the ground, rendering them incapable of walking efficiently. The pathogenesis of FOG remains uncertain but is likely attributed to functional perturbations in superficial cortical and deep locomotion regions. FOG tends to manifest more prominently during complex walking, such as turning, than during simple straight forward walking, and the reasons for this phenomenon remain unclear. Unfortunately, effective methods for overcoming this ambulatory issue has yet to be identified, and quantifying paroxysmal gait spells proves challenging with clinical rating alone; thus, a scientific tool is warranted. In this 3-year proposal, the investigators plan to address these challenges comprehensively.

This description comes directly from the study's public registry record.

Talk to the study team

Chon-Haw Tsai, PHD  ·  8864-22052121  ·  008079@tool.caaumed.org.tw

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Locations (1)

China Medical University Hospital/Neuro DepartTaichung, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT06505460