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Study identifier: NCT06504511 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom

Condition: SCN1A · Dravet Syndrome · Epilepsy  ·  Sponsor: NHS Greater Glasgow and Clyde

PhaseN/A
Planned participants400
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The aims of this prospective natural history study are to define the seizure, neuro-developmental, and behavioural characteristics of SCN1A-related epilepsies/Dravet syndrome in children and adults longitudinally over a period of three years. In addition, this study will compare missense and truncating genotypes in terms of i) rates of change of countable convulsive seizures per month and ii) neurodevelopmental outcome and trajectories.

This description comes directly from the study's public registry record.

Talk to the study team

Kirsty Hendry, PhD  ·  0141 451 5888  ·  SCN1AHorizons@glasgow.ac.uk

Andreas Brunklaus, MD PhD  ·  0141 451 5888  ·  andreas.brunklaus@glasgow.ac.uk

Always discuss trial participation with your own doctor first.

Locations (1)

Royal Hospital for ChildrenGlasgow, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06504511