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Study identifier: NCT06503003 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Non-ablative Diode Laser Therapy for Genitourinary Syndrome of Menopause: A Prospective Study on Efficacy, Safety, and Quality of Life and Sexuality Impact

Condition: Genitourinary Syndrome of Menopause  ·  Sponsor: University of Cagliari

PhaseN/A
Planned participants50
Who can joinFemale, 45 Years to 73 Years
Healthy volunteersNo

About this study

The goal of this observational study is to evaluate the efficacy, safety, and impact on quality of life and sexuality of non-ablative dual-wavelength diode laser treatments in managing Genitourinary Syndrome of Menopause (GSM) in sexually active post-menopausal women who cannot use or have not benefited from local estrogen-based therapies. The main questions it aims to answer are: Does non-ablative dual-wavelength diode laser therapy improve vaginal dryness, burning sensation, and dyspareunia in post-menopausal women? What is the impact of this therapy on the vaginal health index and sexual function? Researchers will compare the laser-treated group to their baseline measurements to see if non-ablative dual-wavelength diode laser therapy effectively treats GSM. Participants will: Undergo three monthly sessions of dual-wavelength diode laser therapy. Participate in follow-up evaluations at three and six months post-treatment. Complete self-assessments of GSM symptoms and questionnaires evaluating sexual function and quality of life at each follow-up. This study aims to provide preliminary evidence that non-ablative dual-wavelength diode laser therapy is a safe and effective non-hormonal treatment for GSM, addressing a gap in existing treatments for women who cannot use or have not benefited from hormonal therapies.

This description comes directly from the study's public registry record.

Talk to the study team

Stefano Angioni  ·  +3907051093399  ·  sangioni@yahoo.it

Always discuss trial participation with your own doctor first.

Locations (1)

Division of Gynecology and Obstetrics Department of Surgical Sciences, University of Cagliari, Cagliari, ItalyCagliari, CA, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06503003