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Study identifier: NCT06500884 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

Condition: Multiple Myeloma  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 2
Planned participants210
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to identify preventive treatments that can minimize the occurrence, severity, and duration of talquetamab-related taste changes (dysgeusia), during the prophylaxis (preventive) treatment phase, to better characterize the signs or symptoms of talquetamab-related taste changes and to better characterize the signs or symptoms of ramantamig-related taste changes.

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (38)

University of California San FranciscoSan Francisco, California, United StatesRecruiting
Colorado Blood Cancer InstituteDenver, Colorado, United StatesRecruiting
Yale University School Of MedicineNew Haven, Connecticut, United StatesRecruiting
Icahn School of Medicine at Mt. SinaiNew York, New York, United StatesRecruiting
University of Rochester Medical CenterRochester, New York, United StatesRecruiting
Duke University Medical CenterDurham, North Carolina, United StatesRecruiting
University Hospitals Cleveland Medical CenterCleveland, Ohio, United StatesRecruiting
Virginia Commonwealth University - Massey Cancer CenterRichmond, Virginia, United StatesRecruiting
University of WashingtonSeattle, Washington, United StatesRecruiting
Hospitais Integrados da Gavea SA DF StarBrasília, BrazilRecruiting
Fundacao Universidade de Caxias do SulCaxias do Sul, BrazilRecruiting
Hospital Erasto Gaertner- Liga Paranaense de Combate ao CancerCuritiba, BrazilRecruiting

+ 26 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06500884